Product Data Sheet

Pirfenidone

Catalog No. A16209

main product photo
Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II.
Adooq's Pirfenidone has been cited by 1 publications
  • Yan Yang, .et al. , J Thorac Dis, 2024, Feb 29;16(2):1128-1140 PMID: 38505034
  • Chemical Information
    Catalog NumA16209
    M. Wt185.22
    FormulaC12H11NO
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.53179-13-8
    SynonymsAMR69, AMR-69, AMR 69
    SMILESO=C1C=CC(C)=CN1C2=CC=CC=C2
    Biological Activity
    DescriptionPirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II.
    Targets
    TargetValue
    Solubility
    In vitro (25°C) DMSO37 mg/mL (199.76 mM)
    WaterInsoluble
    Ethanol37 mg/mL (199.76 mM)
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM53.99 mL269.95 mL539.9 mL
    0.5 mM10.8 mL53.99 mL107.98 mL
    1 mM5.4 mL26.99 mL53.99 mL
    5 mM1.08 mL5.4 mL10.8 mL
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