Product Data Sheet

JW74

Catalog No. A16219

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JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.
Adooq's JW74 has been cited by 1 publications
  • Yang JM, .et al. , Toxicology, 2018, Dec 1;410:65-72 PMID: 30205152
  • Chemical Information
    Catalog Num A16219
    M. Wt 456.52
    Formula C24H20N6O2S
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 863405-60-1
    Synonyms JW-74, JW 74
    SMILES CC1=CC=C(C2=NOC(CSC3=NN=C(C4=CC=NC=C4)N3C5=CC=C(OC)C=C5)=N2)C=C1
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.
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