Product Data Sheet
Homatropine methylbromide
Catalog No. A16577
Homatropine methylbromide is a muscarinic acetylcholine receptor (mAChR) antagonist that demonstrates significant inhibitory activity on endothelial and smooth muscle muscarinic receptors, with an IC50 of 162 nM in WKY-E and SHR-E models. This compound is utilized in research applications focused on studying the effects of mAChR modulation in various physiological and pathological conditions. It serves as a valuable tool for investigating the role of muscarinic signaling in smooth muscle contraction and vascular function.
Chemical Information
| Catalog Num | A16577 |
|---|---|
| M. Wt | 370.28 |
| Formula | C17H24BrNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 80-49-9 |
| Synonyms | Homatropine methobromide |
| SMILES | C[N+]1([C@@H]2C[C@@H](OC(C(O)C3=CC=CC=C3)=O)C[C@H]1CC2)C.[Br-] |
Biological Activity
| Description | Homatropine methylbromide is a muscarinic acetylcholine receptor (mAChR) antagonist that demonstrates significant inhibitory activity on endothelial and smooth muscle muscarinic receptors, with an IC50 of 162 nM in WKY-E and SHR-E models. This compound is utilized in research applications focused on studying the effects of mAChR modulation in various physiological and pathological conditions. It serves as a valuable tool for investigating the role of muscarinic signaling in smooth muscle contraction and vascular function. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
