Product Data Sheet
Isatin
Catalog No. A16586
Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 value of 3 μM, making it a valuable tool in neuropharmacological research. In addition to its MAO inhibitory activity, isatin also interacts with central benzodiazepine receptors (IC50 against clonazepam, 123 μM) and acts as an antagonist of both atrial natriuretic peptide-stimulated and nitric oxide-stimulated guanylate cyclase activity. This compound's multiple mechanisms of action highlight its potential in studying the serotonergic system and its related pathways in various biological contexts.
Chemical Information
| Catalog Num | A16586 |
|---|---|
| M. Wt | 147.13 |
| Formula | C8H5NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 91-56-5 |
| Synonyms | Indoline-2,3-dione |
| SMILES | O=C1NC2=C(C=CC=C2)C1=O |
Biological Activity
| Description | Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 value of 3 μM, making it a valuable tool in neuropharmacological research. In addition to its MAO inhibitory activity, isatin also interacts with central benzodiazepine receptors (IC50 against clonazepam, 123 μM) and acts as an antagonist of both atrial natriuretic peptide-stimulated and nitric oxide-stimulated guanylate cyclase activity. This compound's multiple mechanisms of action highlight its potential in studying the serotonergic system and its related pathways in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
