Product Data Sheet

STF-083010

Catalog No. A16720

main product photo
STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
Adooq's STF-083010 has been cited by 1 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Chemical Information
    Catalog NumA16720
    M. Wt317.38
    FormulaC15H11NO3S2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.307543-71-1
    SynonymsSTF083010, STF 083010
    SMILESO=S(C1=CC=CS1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
    Biological Activity
    DescriptionSTF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
    Solubility
    In vitro (25°C) DMSO54 mg/mL (170.14 mM)
    WaterInsoluble
    EthanolInsoluble
    In vivo 2% DMSO+40%PEG 300+5% Tween80 +ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM31.51 mL157.54 mL315.08 mL
    0.5 mM6.3 mL31.51 mL63.02 mL
    1 mM3.15 mL15.75 mL31.51 mL
    5 mM0.63 mL3.15 mL6.3 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.