Succinylsulfathiazole
Catalog No. A16723

Succinylsulfathiazole is a sulfonamide antibiotic that targets bacterial folate synthesis, providing localized, gut-specific antibacterial activity. This compound effectively reduces coliform counts, suppresses intestinal bacterial growth, and depletes gut folate-producing bacteria while modulating hepatic mTOR signaling. Succinylsulfathiazole is utilized in research focused on nutrient deficiency and its implications, as it induces folate deficiency and related nutritional symptoms in animal models such as rats and C57BL/6 mice. This antibiotic is valuable for understanding the mechanisms of gut flora modulation and the impact on nutritional status.
Chemical Information
| Catalog Num | A16723 |
|---|---|
| M. Wt | 355.39 |
| Formula | C13H13N3O5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 116-43-8 |
| Synonyms | Succinylsulphathiazole |
| SMILES | O=C(O)CCC(NC1=CC=C(S(=O)(NC2=NC=CS2)=O)C=C1)=O |
Biological Activity
| Description | Succinylsulfathiazole is a sulfonamide antibiotic that targets bacterial folate synthesis, providing localized, gut-specific antibacterial activity. This compound effectively reduces coliform counts, suppresses intestinal bacterial growth, and depletes gut folate-producing bacteria while modulating hepatic mTOR signaling. Succinylsulfathiazole is utilized in research focused on nutrient deficiency and its implications, as it induces folate deficiency and related nutritional symptoms in animal models such as rats and C57BL/6 mice. This antibiotic is valuable for understanding the mechanisms of gut flora modulation and the impact on nutritional status. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


