Product Data Sheet

Atuveciclib (BAY-1143572)

Catalog No. A16810

main product photo
Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.
Adooq's Atuveciclib (BAY-1143572) has been cited by 1 publications
  • Cole Schonhofer, .et al. , Biochem Pharmacol, 2021, Apr;186:114462 PMID: 33577894
  • Chemical Information
    Catalog NumA16810
    M. Wt387.43
    FormulaC18H18FN5O2S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1414943-88-6
    SynonymsBAY 1143572, BAY-1143572
    SMILESO=S(C)(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)=N
    Biological Activity
    DescriptionAtuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.
    Targets
    TargetValue
    Solubility
    In vitro DMSO69 mg/mL (178.09 mM)
    WaterInsoluble
    EthanolInsoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM25.81 mL129.06 mL258.11 mL
    0.5 mM5.16 mL25.81 mL51.62 mL
    1 mM2.58 mL12.91 mL25.81 mL
    5 mM0.52 mL2.58 mL5.16 mL
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    SHIPPING AND STORAGE
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