Product Data Sheet
1A-116
Catalog No. A16965
1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.
| Catalog Num | A16965 |
|---|---|
| M. Wt | 307.32 |
| Formula | C16H16F3N3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1430208-73-3 |
| Synonyms | 1A116, 1A 116 |
| SMILES | N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| Discription | 1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo. |
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