Product Data Sheet

PX20606 trans-isomer

Catalog No. A16997

main product photo
PX20606, also known as PX-102, is a FXR agonist. It induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice.
Chemical Information
Catalog NumA16997
M. Wt554.85
FormulaC29H22Cl3NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1268244-85-4
SynonymsPX-20606, PX 20606, PX-102, PX 102, PX10
SMILESO=C(O)C1=CC=C([C@@H]2[C@@H](C3=CC=C(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)C=C3Cl)C2)C=C1
Biological Activity
DescriptionPX20606, also known as PX-102, is a FXR agonist. It induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice.
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