Product Data Sheet

COH29

Catalog No. A17168

main product photo
COH29 is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity.
Chemical Information
Catalog Num A17168
M. Wt 420.43
Formula C22H16N2O5S
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1190932-38-7
Synonyms COH 29, COH-29
SMILES OC1=C(O)C=C(C(NC2=NC(C3=CC(O)=C(O)C=C3)=C(C4=CC=CC=C4)S2)=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription COH29 is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity.
Solubility
In vitro DMSO 40 mg/mL (95.13 mM)
Water 59 mg/mL (140.32 mM)
Ethanol 10 mg/mL (23.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.79 mL 118.93 mL 237.85 mL
0.5 mM 4.76 mL 23.79 mL 47.57 mL
1 mM 2.38 mL 11.89 mL 23.79 mL
5 mM 0.48 mL 2.38 mL 4.76 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.