Product Data Sheet

Remdesivir

Catalog No. A17170

main product photo
Remdesivir, also known as GS-5734, inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h.
Adooq's Remdesivir has been cited by 3 publications
  • Hyeon-Min Cha, .et al. , ACS Infect Dis, 2023, Apr 14;9(4):1033-1045 PMID: 36912867
  • Haidar Saify Nabiabad, .et al. , Chem Biol Drug Des, 2022, Feb;99(2):233-246 PMID: 34714580
  • Kuoyuan Cheng, .et al. , bioRxiv, 2021, Jan 28 PMID: 33532779
  • Chemical Information
    Catalog Num A17170
    M. Wt 602.58
    Formula C27H35N6O8P
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 1809249-37-3
    Synonyms GS-5734, GS 5734, GS5734
    SMILES CCC(CC)COC([C@H](C)N[P@](OC[C@H]1O[C@](C2=CC=C3N2N=CC=C3N)(C#N)[C@H](O)[C@@H]1O)(OC4=CC=CC=C4)=O)=O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Remdesivir, also known as GS-5734, inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h.
    Solubility
    In vitro DMSO 96 mg/mL (159.31 mM)
    Water Insoluble
    Ethanol 15 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 16.6 mL 82.98 mL 165.95 mL
    0.5 mM 3.32 mL 16.6 mL 33.19 mL
    1 mM 1.66 mL 8.3 mL 16.6 mL
    5 mM 0.33 mL 1.66 mL 3.32 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.