Product Data Sheet
Mexiletine hydrochloride
Catalog No. A17349
Mexiletine hydrochloride is an orally active antiarrhythmic agent that primarily functions by inhibiting sodium channels, with an IC50 value of 75±8 μM for tonic block and 23.6±2.8 μM for use-dependent block. This compound has demonstrated efficacy in the management of myotonia and neuropathic pain, making it a valuable tool in both cardiovascular and neurological research. Its ability to modulate ion channel activity allows for insights into the mechanisms of arrhythmias and other related disorders.
Chemical Information
| Catalog Num | A17349 |
|---|---|
| M. Wt | 215.72 |
| Formula | C11H18ClNO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 5370-01-4 |
| Synonyms | KOE-1173 hydrochloride |
| SMILES | CC(N)COC1=C(C)C=CC=C1C.[H]Cl |
Biological Activity
| Description | Mexiletine hydrochloride is an orally active antiarrhythmic agent that primarily functions by inhibiting sodium channels, with an IC50 value of 75±8 μM for tonic block and 23.6±2.8 μM for use-dependent block. This compound has demonstrated efficacy in the management of myotonia and neuropathic pain, making it a valuable tool in both cardiovascular and neurological research. Its ability to modulate ion channel activity allows for insights into the mechanisms of arrhythmias and other related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
