Product Data Sheet

Carbenoxolone Sodium

Catalog No. A17382

main product photo
Glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.
Chemical Information
Catalog Num A17382
M. Wt 614.73
Formula C34H48Na2O7
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 7421-40-1
Synonyms Biogastrone; Bioral; Carbenoxolone sodium; Duogastrone; Pyrogastrone; Sanodin
SMILES CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CC[C@](C([O-])=O)(C[C@]2(C1=C3)[H])C)C)C)4C)5[H])[C@@H](OC(CCC([O-])=O)=O)CC[C@]5(C)[C@@]4([H])C3=O.[Na+].[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.
Solubility
In vitro DMSO Warmed: 22 mg/mL (35.78 mM)
Water Warmed: 95 mg/mL (154.54 mM)
Ethanol Warmed: 30 mg/mL (48.8 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.27 mL 81.34 mL 162.67 mL
0.5 mM 3.25 mL 16.27 mL 32.53 mL
1 mM 1.63 mL 8.13 mL 16.27 mL
5 mM 0.33 mL 1.63 mL 3.25 mL
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.