Product Data Sheet
Prochlorperazine dimaleate
Catalog No. A17405
Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
Chemical Information
| Catalog Num | A17405 |
|---|---|
| M. Wt | 606.09 |
| Formula | C28H32ClN3O8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 84-02-6 |
| Synonyms | |
| SMILES | O=C(O)/C=C\C(O)=O.CN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(Cl)C=C24)CC1.O=C(O)/C=C\C(O)=O |
Biological Activity
| Description | Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
