Product Data Sheet
D-Arabinopyranose
Catalog No. A17538
D-Arabinopyranose is a rare aldo-pentose that serves as a precursor to D-arabinose in its open-chain form. This compound exhibits significant biological activity, including antidepressant effects and growth inhibition in Caenorhabditis elegans with an IC50 of 7.5 mM. D-Arabinose penetrates the blood-brain barrier, specifically modulating the metabolism of D-ribose and D-fructose, while also demonstrating antibacterial properties by inhibiting biofilm synthesis. Additionally, it activates the ACSS2-PPARγ/TFEB-CRTC1 axis via the lysosomal AXIN-LKB1-AMPK pathway, leading to antidepressant-like outcomes.
Chemical Information
| Catalog Num | A17538 |
|---|---|
| M. Wt | 150.13 |
| Formula | C5H10O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 28697-53-2 |
| Synonyms | |
| SMILES | OC1[C@H]([C@@H]([C@@H](CO1)O)O)O |
Biological Activity
| Description | D-Arabinopyranose is a rare aldo-pentose that serves as a precursor to D-arabinose in its open-chain form. This compound exhibits significant biological activity, including antidepressant effects and growth inhibition in Caenorhabditis elegans with an IC50 of 7.5 mM. D-Arabinose penetrates the blood-brain barrier, specifically modulating the metabolism of D-ribose and D-fructose, while also demonstrating antibacterial properties by inhibiting biofilm synthesis. Additionally, it activates the ACSS2-PPARγ/TFEB-CRTC1 axis via the lysosomal AXIN-LKB1-AMPK pathway, leading to antidepressant-like outcomes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
