Product Data Sheet

Econazole

Catalog No. A17655

main product photo
Econazole is an orally active imidazole antifungal agent that primarily targets the cytochrome P-450 enzyme system. It demonstrates significant antifungal activity against various fungi and some Gram-positive bacteria, while lacking efficacy against Gram-negative bacteria. Additionally, econazole is known to inhibit prostaglandin synthesis and may induce hepatotoxicity, making it valuable in the study of antifungal resistance and the mechanisms of liver injury.
Chemical Information
Catalog NumA17655
M. Wt381.68
FormulaC18H15Cl3N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.27220-47-9
Synonyms(±)-Econazol
SMILESClC1=CC=C(C(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
Biological Activity
DescriptionEconazole is an orally active imidazole antifungal agent that primarily targets the cytochrome P-450 enzyme system. It demonstrates significant antifungal activity against various fungi and some Gram-positive bacteria, while lacking efficacy against Gram-negative bacteria. Additionally, econazole is known to inhibit prostaglandin synthesis and may induce hepatotoxicity, making it valuable in the study of antifungal resistance and the mechanisms of liver injury.
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