Product Data Sheet
2'-Deoxyuridine (dU, 2'-dU)
Catalog No. A17664
2'-Deoxyuridine is a nucleoside that serves as a precursor for the antiviral agent Edoxudine and plays a crucial role in nucleotide metabolism. It has been shown to increase chromosome breakage and reduce thymidylate synthase activity, highlighting its significance in DNA synthesis research. Additionally, 2'-deoxyuridine has demonstrated the ability to reduce microglial activation and improve oxidative stress in models of Aβ25-35-induced brain injury, making it a valuable tool for Alzheimer's disease research.
Chemical Information
| Catalog Num | A17664 |
|---|---|
| M. Wt | 228.20 |
| Formula | C9H12N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 951-78-0 |
| Synonyms | |
| SMILES | O=C(N1)N([C@H]2C[C@H](O)[C@@H](CO)O2)C=CC1=O |
Biological Activity
| Description | 2'-Deoxyuridine is a nucleoside that serves as a precursor for the antiviral agent Edoxudine and plays a crucial role in nucleotide metabolism. It has been shown to increase chromosome breakage and reduce thymidylate synthase activity, highlighting its significance in DNA synthesis research. Additionally, 2'-deoxyuridine has demonstrated the ability to reduce microglial activation and improve oxidative stress in models of Aβ25-35-induced brain injury, making it a valuable tool for Alzheimer's disease research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
