Amiloride
Catalog No. A17684

Amiloride is an inhibitor of epithelial sodium channels (ENaC) and the urokinase-type plasminogen activator receptor (uPAR). This compound has been shown to induce apoptosis through its modulation of sodium ion transport and intracellular signaling pathways. Research applications include studies on renal function, cancer cell metabolism, and the investigation of ion channel-related diseases. Additionally, Amiloride has been explored as a potential therapeutic agent in various pathophysiological conditions.
Chemical Information
| Catalog Num | A17684 |
|---|---|
| M. Wt | 229.63 |
| Formula | C6H8ClN7O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2609-46-3 |
| Synonyms | MK-870 |
| SMILES | O=C(C1=NC(Cl)=C(N)N=C1N)NC(N)=N |
Biological Activity
| Description | Amiloride is an inhibitor of epithelial sodium channels (ENaC) and the urokinase-type plasminogen activator receptor (uPAR). This compound has been shown to induce apoptosis through its modulation of sodium ion transport and intracellular signaling pathways. Research applications include studies on renal function, cancer cell metabolism, and the investigation of ion channel-related diseases. Additionally, Amiloride has been explored as a potential therapeutic agent in various pathophysiological conditions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


