Product Data Sheet
Chlorpromazine
Catalog No. A17763
Chlorpromazine is an orally active antipsychotic agent that primarily antagonizes D2 dopamine and 5-HT2A serotonin receptors, making it effective in the treatment of schizophrenia and other psychiatric conditions. Additionally, chlorpromazine exhibits anti-cancer properties through mechanisms such as inhibition of tumor proliferation, induction of autophagy, cell cycle arrest at the G2-M phase, and suppression of tumor growth and metastasis. It also blocks hNav1.7 and HERG potassium channels, which has implications for analgesic and cardiac arrhythmia research. Furthermore, chlorpromazine inhibits clathrin-mediated endocytosis, expanding its potential applications in biomedical research.
Chemical Information
| Catalog Num | A17763 |
|---|---|
| M. Wt | 318.86 |
| Formula | C17H19ClN2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 50-53-3 |
| Synonyms | |
| SMILES | CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13 |
Biological Activity
| Description | Chlorpromazine is an orally active antipsychotic agent that primarily antagonizes D2 dopamine and 5-HT2A serotonin receptors, making it effective in the treatment of schizophrenia and other psychiatric conditions. Additionally, chlorpromazine exhibits anti-cancer properties through mechanisms such as inhibition of tumor proliferation, induction of autophagy, cell cycle arrest at the G2-M phase, and suppression of tumor growth and metastasis. It also blocks hNav1.7 and HERG potassium channels, which has implications for analgesic and cardiac arrhythmia research. Furthermore, chlorpromazine inhibits clathrin-mediated endocytosis, expanding its potential applications in biomedical research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
