Product Data Sheet

Proguanil

Catalog No. A17797

main product photo
Proguanil is a potent dihydrofolate reductase (DHFR) inhibitor, primarily utilized in antimalarial research. Upon administration, it is metabolized to Cycloguanil, its active form, enhancing its efficacy against Plasmodium species. This compound is essential for studying the biochemical pathways of folate metabolism and developing therapeutic strategies against malaria.
Chemical Information
Catalog NumA17797
M. Wt253.73
FormulaC11H16ClN5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.500-92-5
Synonyms
SMILESN=C(NC1=CC=C(Cl)C=C1)NC(NC(C)C)=N
Biological Activity
DescriptionProguanil is a potent dihydrofolate reductase (DHFR) inhibitor, primarily utilized in antimalarial research. Upon administration, it is metabolized to Cycloguanil, its active form, enhancing its efficacy against Plasmodium species. This compound is essential for studying the biochemical pathways of folate metabolism and developing therapeutic strategies against malaria.
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SHIPPING AND STORAGE
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