Product Data Sheet

Penbutolol sulfate

Catalog No. A17893

main product photo
Penbutolol sulfate is a potent adrenergic receptor inhibitor, primarily acting as a β-adrenoceptor and 5-HT receptor antagonist, with Ki values of 11.6 nM and 11.9 nM for 5-HT in rat cornu ammonis 1 (CA1) and human CA3 regions, respectively. This compound demonstrates significant biological activity through modulation of neurotransmitter signaling pathways, making it valuable for research applications involving cardiovascular studies and neuropharmacology.
Chemical Information
Catalog NumA17893
M. Wt340.47
FormulaC18H29NO2 . 1/2 H2O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.38363-32-5
Synonyms(-)-Terbuclomine
SMILESO[C@@H](CNC(C)(C)C)COC1=CC=CC=C1C2CCCC2.O=S(O)(O)=O
Biological Activity
DescriptionPenbutolol sulfate is a potent adrenergic receptor inhibitor, primarily acting as a β-adrenoceptor and 5-HT receptor antagonist, with Ki values of 11.6 nM and 11.9 nM for 5-HT in rat cornu ammonis 1 (CA1) and human CA3 regions, respectively. This compound demonstrates significant biological activity through modulation of neurotransmitter signaling pathways, making it valuable for research applications involving cardiovascular studies and neuropharmacology.
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SHIPPING AND STORAGE
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