Product Data Sheet

Hydroflumethiazide

Catalog No. A17897

main product photo
Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).
Chemical Information
Catalog Num A17897
M. Wt 331.29
Formula C8H8F3N3O4S2
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 135-09-1
Synonyms Hydroflumethiazide; Diuredemina; Glomerulin; Hidroflumetiazid; Diurometon; Flutizide;
SMILES C1NC2=C(C=C(C(=C2)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).
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SHIPPING AND STORAGE
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