Product Data Sheet
Glycylglycine
Catalog No. A17934
Glycylglycine, an iNOS inhibitor, is a dipeptide that serves as a non-selective glycylglycine dipeptidase substrate. It effectively crosses cell membranes through passive diffusion and is subsequently hydrolyzed to glycine, which participates in energy metabolism and antioxidant defense. This compound promotes the proliferation of spermatogonial stem cells (SSCs), mitigates astrocyte overactivation, and reduces nitric oxide (NO) release while enhancing the expression of neurotrophic factors such as PDGFA, FGF2, and CNTF, thereby supporting nerve myelin repair. Glycylglycine is valuable in research on male reproductive biology and neurodegenerative diseases, including the investigation of neuroprotective mechanisms in conditions like multiple sclerosis.
Chemical Information
| Catalog Num | A17934 |
|---|---|
| M. Wt | 132.12 |
| Formula | C4H8N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 556-50-3 |
| Synonyms | Gly-Gly; H-Gly-Gly-OH |
| SMILES | NCC(=O)NCC(O)=O |
Biological Activity
| Description | Glycylglycine, an iNOS inhibitor, is a dipeptide that serves as a non-selective glycylglycine dipeptidase substrate. It effectively crosses cell membranes through passive diffusion and is subsequently hydrolyzed to glycine, which participates in energy metabolism and antioxidant defense. This compound promotes the proliferation of spermatogonial stem cells (SSCs), mitigates astrocyte overactivation, and reduces nitric oxide (NO) release while enhancing the expression of neurotrophic factors such as PDGFA, FGF2, and CNTF, thereby supporting nerve myelin repair. Glycylglycine is valuable in research on male reproductive biology and neurodegenerative diseases, including the investigation of neuroprotective mechanisms in conditions like multiple sclerosis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
