Product Data Sheet
Sulfathiazole sodium
Catalog No. A18117
Sulfathiazole sodium is an orally active antibiotic that functions as an endocrine disruptor by targeting the steroidogenic pathway, specifically enhancing CYP19 activity in human adrenal cancer cells (H295R) and upregulating the expression of mRNAs for CYP17, CYP19, and 3β-HSD. It significantly increases the production of 17-estradiol (E2) and exhibits endocrine-disrupting effects in aquatic organisms, such as the Japanese medaka fish. Additionally, sulfathiazole sodium serves as a cathodic corrosion inhibitor, effectively reducing copper corrosion in the presence of chloride ions through both chemical and physical adsorption mechanisms.
Chemical Information
| Catalog Num | A18117 |
|---|---|
| M. Wt | 277.30 |
| Formula | C9H8N3NaO2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 144-74-1 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(N)C=C1)([N-]C2=NC=CS2)=O.[Na+] |
Biological Activity
| Description | Sulfathiazole sodium is an orally active antibiotic that functions as an endocrine disruptor by targeting the steroidogenic pathway, specifically enhancing CYP19 activity in human adrenal cancer cells (H295R) and upregulating the expression of mRNAs for CYP17, CYP19, and 3β-HSD. It significantly increases the production of 17-estradiol (E2) and exhibits endocrine-disrupting effects in aquatic organisms, such as the Japanese medaka fish. Additionally, sulfathiazole sodium serves as a cathodic corrosion inhibitor, effectively reducing copper corrosion in the presence of chloride ions through both chemical and physical adsorption mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
