Product Data Sheet
Bucladesine calcium
Catalog No. A18132
Bucladesine calcium is a cell-permeable analog of cyclic AMP (cAMP), functioning as an apoptosis inducer primarily through the activation of cAMP-dependent protein kinase (PKA). By elevating intracellular cAMP levels, it inhibits phosphodiesterase (PDE) activity, thereby stabilizing cAMP concentrations and promoting apoptosis in targeted cells. This compound is widely utilized in research applications investigating cell signaling pathways, PKA-mediated processes, and mechanisms underlying programmed cell death.
Chemical Information
| Catalog Num | A18132 |
|---|---|
| M. Wt | 488.42 |
| Formula | C18H23Ca0.5N5O8P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 938448-87-4 |
| Synonyms | Dibutyryl cAMP calcium salt; DBcAMP calcium salt |
| SMILES | O=C(CCC)O[C@H]1[C@H](N2C(N=CN=C3NC(CCC)=O)=C3N=C2)O[C@@](CO4)([H])[C@@]1([H])OP4([O-])=O.[Ca2+] |
Biological Activity
| Description | Bucladesine calcium is a cell-permeable analog of cyclic AMP (cAMP), functioning as an apoptosis inducer primarily through the activation of cAMP-dependent protein kinase (PKA). By elevating intracellular cAMP levels, it inhibits phosphodiesterase (PDE) activity, thereby stabilizing cAMP concentrations and promoting apoptosis in targeted cells. This compound is widely utilized in research applications investigating cell signaling pathways, PKA-mediated processes, and mechanisms underlying programmed cell death. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
