Product Data Sheet
Kasugamycin hydrochloride hydrate
Catalog No. A18193
Kasugamycin hydrochloride hydrate is an antibiotic that targets 30S and 70S ribosomal subunits, selectively inhibiting canonical translation initiation by mimicking mRNA nucleotides and disrupting tRNA binding. Its anti-infective properties are particularly notable, as it enhances the sensitivity of mycobacteria to Rifampicin in vitro and within mouse infection models. This compound is valuable for research applications related to antibiotic mechanisms, bacterial resistance, and the study of ribosomal function in protein synthesis.
Chemical Information
| Catalog Num | A18193 |
|---|---|
| M. Wt | 433.84 |
| Formula | C14H28ClN3O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 200132-83-8 |
| Synonyms | Ksg hydrochloride hydrate |
| SMILES | OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.Cl.O |
Biological Activity
| Description | Kasugamycin hydrochloride hydrate is an antibiotic that targets 30S and 70S ribosomal subunits, selectively inhibiting canonical translation initiation by mimicking mRNA nucleotides and disrupting tRNA binding. Its anti-infective properties are particularly notable, as it enhances the sensitivity of mycobacteria to Rifampicin in vitro and within mouse infection models. This compound is valuable for research applications related to antibiotic mechanisms, bacterial resistance, and the study of ribosomal function in protein synthesis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
