Product Data Sheet

Thonzonium bromide

Catalog No. A18268

main product photo
Thonzonium bromide is a monocationic surface-active agent with antibacterial properties. It demonstrates the ability to inhibit RANKL-induced osteoclast formation and bone resorption in vitro, while also preventing LPS-induced bone loss in vivo. Thonzonium bromide effectively inhibits proton transport in a dose-dependent manner, with an EC50 of 69 μM. This compound is valuable for research applications in bone health and antibacterial studies.
Chemical Information
Catalog NumA18268
M. Wt591.71
FormulaC32H55BrN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.553-08-2
Synonyms
SMILESCCCCCCCCCCCCCCCC[N+](C)(CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=N2)C.[Br-]
Biological Activity
DescriptionThonzonium bromide is a monocationic surface-active agent with antibacterial properties. It demonstrates the ability to inhibit RANKL-induced osteoclast formation and bone resorption in vitro, while also preventing LPS-induced bone loss in vivo. Thonzonium bromide effectively inhibits proton transport in a dose-dependent manner, with an EC50 of 69 μM. This compound is valuable for research applications in bone health and antibacterial studies.
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