Product Data Sheet
Adapalene sodium salt
Catalog No. A18305
Adapalene sodium salt is a potent retinoic acid receptor (RAR) agonist, demonstrating significant binding affinity with AC50 values of 2.3 nM for RARβ, 9.3 nM for RARγ, and 22 nM for RARα. This third-generation synthetic retinoid is primarily utilized in acne research but has also been identified to inhibit the enzymatic activity of glutamate oxaloacetate transaminase 1 (GOT1) in a non-competitive manner. Additionally, adapalene sodium salt exhibits anti-tumor activity, making it valuable for diverse biological studies.
Chemical Information
| Catalog Num | A18305 |
|---|---|
| M. Wt | 434.50 |
| Formula | C28H27NaO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 911110-93-5 |
| Synonyms | CD 271 sodium salt |
| SMILES | O=C(C1=CC2=CC=C(C3=CC=C(OC)C(C45C[C@@H](C[C@H](C6)C5)C[C@@H]6C4)=C3)C=C2C=C1)[O-].[Na+] |
Biological Activity
| Description | Adapalene sodium salt is a potent retinoic acid receptor (RAR) agonist, demonstrating significant binding affinity with AC50 values of 2.3 nM for RARβ, 9.3 nM for RARγ, and 22 nM for RARα. This third-generation synthetic retinoid is primarily utilized in acne research but has also been identified to inhibit the enzymatic activity of glutamate oxaloacetate transaminase 1 (GOT1) in a non-competitive manner. Additionally, adapalene sodium salt exhibits anti-tumor activity, making it valuable for diverse biological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
