Product Data Sheet

IDH1 Inhibitor 2

Catalog No. A18420

main product photo
DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.
Adooq's IDH1 Inhibitor 2 has been cited by 1 publications
  • Derek Dang, .et al. , Cancer Cell, 2025, Jun 9;43(6):1159-1174 PMID: 40378837
  • Chemical Information
    Catalog NumA18420
    M. Wt406.48
    FormulaC26H22N4O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.2244895-42-7
    Synonyms
    SMILESN#CC1=C[C@@]2(C3=CC=CC=C3)[C@](CCC4=C2N=C(NC5=CC=CC=C5)N=C4)([H])[C@H](C)C1=O
    Biological Activity
    DescriptionDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.
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