Product Data Sheet

ESI-05

Catalog No. A18644

main product photo
ESI-05 (NSC 116966) is a specific antagonist of EPAC2 (exchange protein directly activated by cAMP 2), with an IC50 of 0.4 ?M. ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 as well as EAPC2 mediated Rap1 activation.
Adooq's ESI-05 has been cited by 1 publications
  • Yuri A Blednov, .et al. , Neuropharmacology, 2024, Jun 13:257:110035 PMID: 38876310
  • Chemical Information
    Catalog NumA18644
    M. Wt274.37
    FormulaC16H18O2S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.5184-64-5
    SynonymsESI05, ESI 05
    SMILESO=S(C1=C(C)C=C(C)C=C1C)(C2=CC=C(C)C=C2)=O
    Biological Activity
    DescriptionESI-05 (NSC 116966) is a specific antagonist of EPAC2 (exchange protein directly activated by cAMP 2), with an IC50 of 0.4 ?M. ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 as well as EAPC2 mediated Rap1 activation.
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