Product Data Sheet

APX-115

Catalog No. A18737

main product photo
APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury.
Chemical Information
Catalog NumA18737
M. Wt315.8
FormulaC17H18ClN3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1395946-75-4
SynonymsAPX 115, APX115
SMILESOC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3.Cl
Biological Activity
DescriptionAPX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury.
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