Product Data Sheet

PF-06305591

Catalog No. A18748

main product photo
PF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile.
Chemical Information
Catalog NumA18748
M. Wt274.36
FormulaC15H22N4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1449473-97-5
SynonymsPF06305591, PF 06305591
SMILESCC(C)(C)C1=CC=C(NC([C@H]([C@@H](C)C(N)=O)N)=N2)C2=C1
Biological Activity
DescriptionPF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile.
Targets
TargetValue
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