Product Data Sheet

Iptacopan (LNP023)

Catalog No. A18905

main product photo
LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM).
Adooq's Iptacopan (LNP023) has been cited by 1 publications
  • Wenbin Yang, .et al. , J Clin Invest, 2022, Oct 17;132(20):e157975 PMID: 36250462
  • Chemical Information
    Catalog NumA18905
    M. Wt422.52
    FormulaC25H30N2O4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1644670-37-0
    SynonymsLNP 023, LNP-023
    SMILESO=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1
    Biological Activity
    DescriptionLNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM).
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