Product Data Sheet

GLPG2451

Catalog No. A18919

main product photo
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.
Chemical Information
Catalog NumA18919
M. Wt419.38
FormulaC16H16F3N3O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2055015-61-5
SynonymsGLPG 2451, GLPG-2451
SMILESO=S(C1=CC=C(OC(F)(F)F)C=C1)(C2=CN=C(C(NC[C@@H](O)C)=O)C(N)=C2)=O
Biological Activity
DescriptionGLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.