Product Data Sheet

BSc5371

Catalog No. A19465

main product photo
BSc5371 is a potent and irreversible FLT3 inhibitor, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively.
Chemical Information
Catalog NumA19465
M. Wt485.6
FormulaC24H31N5O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2286419-03-0
SynonymsBSc 5371, BSc-5371
SMILESO=C(C1=C(C)NC(/C=C2C(NC3=C\2C=C(NS(=O)(C=C)=O)C=C3)=O)=C1C)NCCN(CC)CC
Biological Activity
DescriptionBSc5371 is a potent and irreversible FLT3 inhibitor, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively.
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