Product Data Sheet

PD 90780

Catalog No. A19821

main product photo
PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 ?M and 1.8 ?M in PC12 cells and PC12 nnr5 cells, respectively .
Chemical Information
Catalog Num A19821
M. Wt 362.34
Formula C19H14N4O4
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 77422-99-2
Synonyms PD-90780, PD90780
SMILES CN1C2=CC(C(O)=O)=NN2C(C3=CC(NC(C4=CC=CC=C4)=O)=CC=C13)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 ?M and 1.8 ?M in PC12 cells and PC12 nnr5 cells, respectively .
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SHIPPING AND STORAGE
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