Product Data Sheet

PF-06751979

Catalog No. A20066

main product photo
PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.
Chemical Information
Catalog NumA20066
M. Wt455.5
FormulaC18H19F2N5O3S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1818339-66-0
SynonymsPF 06751979, PF06751979
SMILESFC(F)OC1=CN=C(C(NC2=CSC([C@]34CO[C@@H](C)C[C@@]3([H])CSC(N)=N4)=N2)=O)C=C1
Biological Activity
DescriptionPF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.
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SHIPPING AND STORAGE
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