Product Data Sheet

ML364

Catalog No. A20371

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ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity.
Adooq's ML364 has been cited by 1 publications
  • Kevin Bohm, .et al. , Arch Pharm (Weinheim), 2023, Jul;356(7):e2200661 PMID: 37196427
  • Chemical Information
    Catalog NumA20371
    M. Wt517.54
    FormulaC24H18F3N3O3S2
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1991986-30-1
    SynonymsML 364, ML-364
    SMILESO=C(NC1=NC(C2=CC=CC=C2)=CS1)C3=CC=C(C(F)(F)F)C=C3NS(=O)(C4=CC=C(C)C=C4)=O
    Biological Activity
    DescriptionML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity.
    Solubility
    In vitro DMSO45 mg/mL (86.95 mM)
    WaterInsoluble
    Ethanol23 mg/mL (44.44 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM19.32 mL96.61 mL193.22 mL
    0.5 mM3.86 mL19.32 mL38.64 mL
    1 mM1.93 mL9.66 mL19.32 mL
    5 mM0.39 mL1.93 mL3.86 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.