Product Data Sheet

AG-13958

Catalog No. A21175

main product photo
AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).
Chemical Information
Catalog NumA21175
M. Wt467.5
FormulaC26H22FN7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.319460-94-1
SynonymsAG 13958, AG13958, AG-013958, AG 013958, AG013958
SMILESO=C(C1=CC(C)=NN1C)NC2=CC(NC3=CC4=C(C=C3)C(/C=C/C5=NC=CC=C5)=NN4)=CC=C2F
Biological Activity
DescriptionAG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).
Targets
TargetValue
Solubility
In vitro DMSO91 mg/mL (194.64 mM)
WaterInsoluble
EthanolInsoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.39 mL106.95 mL213.9 mL
0.5 mM4.28 mL21.39 mL42.78 mL
1 mM2.14 mL10.7 mL21.39 mL
5 mM0.43 mL2.14 mL4.28 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.