Product Data Sheet

Y-27632

Catalog No. A21448

main product photo
Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
Adooq's Y-27632 has been cited by 3 publications
  • Ryan Lingerak, .et al. , British Journal of Cancer Research, 2025, 8(1): 756-774
  • Sara B Linker, .et al. , Curr Biol, 2022, Nov 21;32(22):4797-4807 PMID: 36228612
  • Renata Santos, .et al. , STAR Protoc, 2022, Mar 17;3(2):101261 PMID: 35313707
  • Chemical Information
    Catalog NumA21448
    M. Wt247.34
    FormulaC14H21N3O
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.146986-50-7
    SynonymsY27632, Y 27632
    SMILESO=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
    Biological Activity
    DescriptionY-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
    Targets
    TargetValue
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    SHIPPING AND STORAGE
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