Product Data Sheet

GDC-0575 dihydrochloride

Catalog No. A21567

main product photo
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
Chemical Information
Catalog Num A21567
M. Wt 450.2
Formula C17H23BrCl2N4O
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1657014-42-0
Synonyms ARRY-575 dihydrochloride, ARRY575, ARRY 575; RG7741 dihydrochloride, RG 7741, RG-7741, GDC0575, GDC 0575
SMILES O=C(C1CC1)NC2=CNC3=C2C(N4C[C@H](N)CCC4)=C(Br)C=C3.[H]Cl.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
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SHIPPING AND STORAGE
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