Product Data Sheet

Momelotinib Mesylate

Catalog No. A21658

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Momelotinib Mesylate (CYT387 Mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, appr 10-fold selectivity versus JAK3.
Adooq's Momelotinib Mesylate has been cited by 1 publications
  • Ghazal Nabil, .et al. , Cancers (Basel), 2021, Feb 20;13(4):898 PMID: 33672756
  • Chemical Information
    Catalog NumA21658
    M. Wt510.57
    FormulaC24H26N6O5S
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.1056636-07-7
    SynonymsCYT387 (Mesylate), CYT 387, CYT-387
    SMILESO=C(C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1)NCC#N.O=S(O)(C)=O
    Biological Activity
    DescriptionMomelotinib Mesylate (CYT387 Mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, appr 10-fold selectivity versus JAK3.
    Targets
    TargetValue
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