Product Data Sheet

Tipifarnib S enantiomer

Catalog No. A21787

main product photo
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
Chemical Information
Catalog NumA21787
M. Wt489.4
FormulaC27H22Cl2N4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.192185-71-0
Synonyms(S)-(-)-R-115777, R115777, R 115777; IND-58359 S enantiomer, IND58359, IND 58359
SMILESO=C1N(C)C2=C(C=C([C@](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1
Biological Activity
DescriptionTipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
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