Product Data Sheet

AMG 837 sodium salt

Catalog No. A21793

main product photo
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
Chemical Information
Catalog NumA21793
M. Wt460.42
FormulaC26H20F3NaO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.865231-45-4
SynonymsAMG837, AMG-837
SMILES[O-]C(C[C@H](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O.[Na+]
Biological Activity
DescriptionAMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
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