Product Data Sheet

JTV-519 free base

Catalog No. A21846

main product photo
TV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.
Chemical Information
Catalog NumA21846
M. Wt424.6
FormulaC25H32N2O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.145903-06-6
SynonymsK201 free base, K 201, K-201, JTV 519, JTV519
SMILESCOC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1
Biological Activity
DescriptionTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.
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SHIPPING AND STORAGE
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