Product Data Sheet

BX471 hydrochloride

Catalog No. A21886

main product photo
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Chemical Information
Catalog NumA21886
M. Wt471.35
FormulaC21H25Cl2FN4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.288262-96-4
SynonymsZK-811752 hydrochloride,ZK811752, ZK 811752,TAK 659, TAK659
SMILESO=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O.[H]Cl
Biological Activity
DescriptionBX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Targets
TargetValue
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SHIPPING AND STORAGE
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