Product Data Sheet

UNC0379 TFA

Catalog No. A22036

main product photo
UNC0379 TFA is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases.
Chemical Information
Catalog NumA22036
M. Wt527.58
FormulaC25H36F3N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1620401-83-3
SynonymsUNC 0379, UNC-0379
SMILESCOC1=C(OC)C=C2C(N=C(N3CCCC3)N=C2NCCCCCN4CCCC4)=C1.O=C(O)C(F)(F)F
Biological Activity
DescriptionUNC0379 TFA is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases.
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