Product Data Sheet

MYC-RIBOTAC

Catalog No. A23948

main product photo
MYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) designed to degrade MYC mRNA by targeting its internal ribosome entry site (IRES). It combines a MYC mRNA-binding moiety with a small molecule that recruits and activates RNase L1. MYC-RIBOTAC reduces MYC mRNA and protein levels, induces apoptosis, and holds promise for antitumor research.
Chemical Information
Catalog NumA23948
M. Wt1067.17
FormulaC55H58N10O11S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.nan
Synonyms
SMILESO=C(NC1=CC(NC(NC2=CC=C(C3=NCCN3)C=C2)=O)=CC(C(NCCOCCOCCOCCOC4=C(O)C=C(/C=C5SC(NC6=CC=CC=C6)=C(C(OCC)=O)C\5=O)C=C4)=O)=C1)NC7=CC=C(C8=NCCN8)C=C7
Biological Activity
DescriptionMYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) designed to degrade MYC mRNA by targeting its internal ribosome entry site (IRES). It combines a MYC mRNA-binding moiety with a small molecule that recruits and activates RNase L1. MYC-RIBOTAC reduces MYC mRNA and protein levels, induces apoptosis, and holds promise for antitumor research.
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SHIPPING AND STORAGE
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