Product Data Sheet
SSTC3
Catalog No. A24015
SSTC3 is a potent activator of casein kinase 1α (CK1α), with a binding affinity (K_d) of 32 nM, and functions as an inhibitor of WNT/β-catenin signaling with an EC₅₀ of 30 nM. Unlike many conventional WNT pathway inhibitors, SSTC3 demonstrates minimal gastrointestinal toxicity, offering a promising therapeutic strategy for targeting WNT-driven cancers with improved safety profiles.
Chemical Information
| Catalog Num | A24015 |
|---|---|
| M. Wt | 518.53 |
| Formula | C23H17F3N4O3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1242422-09-8 |
| Synonyms | |
| SMILES | O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=C(S(=O)(N(C)C4=CC=C(C(F)(F)F)C=C4)=O)C=C3 |
Biological Activity
| Description | SSTC3 is a potent activator of casein kinase 1α (CK1α), with a binding affinity (K_d) of 32 nM, and functions as an inhibitor of WNT/β-catenin signaling with an EC₅₀ of 30 nM. Unlike many conventional WNT pathway inhibitors, SSTC3 demonstrates minimal gastrointestinal toxicity, offering a promising therapeutic strategy for targeting WNT-driven cancers with improved safety profiles. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
