Product Data Sheet

SGC-CK2-1

Catalog No. A24016

main product photo
SGC-CK2-1 is a highly potent, ATP-competitive, and cell-permeable chemical probe that selectively targets casein kinase 2 (CK2), exhibiting IC₅₀ values of 36 nM for CK2α and 16 nM for CK2α′ in the nanoBRET assay. With exclusive selectivity for both human CK2 isoforms, SGC-CK2-1 serves as a valuable tool for studying CK2-related signaling pathways and holds potential for research in neurodegenerative diseases.
Chemical Information
Catalog NumA24016
M. Wt375.43
FormulaC20H21N7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2470424-39-4
Synonyms
SMILESCCC(NC1=CC(NC2=NC3=C(C#N)C=NN3C(NC4CC4)=C2)=CC=C1C)=O
Biological Activity
DescriptionSGC-CK2-1 is a highly potent, ATP-competitive, and cell-permeable chemical probe that selectively targets casein kinase 2 (CK2), exhibiting IC₅₀ values of 36 nM for CK2α and 16 nM for CK2α′ in the nanoBRET assay. With exclusive selectivity for both human CK2 isoforms, SGC-CK2-1 serves as a valuable tool for studying CK2-related signaling pathways and holds potential for research in neurodegenerative diseases.
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